Evidence is accumulating that individual and environmental factors in childhood and adolescence should be considered when investigating adult health and aging-related processes. The data required for this is gathered by comprehensive long-term longitudinal studies. This article describes the protocol of the Zurich Longitudinal Studies, a set of three comprehensive cohort studies on child growth, health, and development that are currently expanding into adulthood. Between 1954 and 1961, 445 healthy infants were enrolled in the first ZLS cohort. Their physical, motor, cognitive, (...) and social development and their environment were assessed comprehensively across childhood, adolescence, and into young adulthood. In the 1970s, two further cohorts were added to the ZLS and assessed with largely matched study protocols: Between 1974 and 1979, the second ZLS cohort included 265 infants, and between 1970 and 2002, the third ZLS cohort included 327 children of participants of the first ZLS cohort. Since 2019, the participants of the three ZLS cohorts have been traced and invited to participate in a first wave of assessments in adulthood to investigate their current health and development. This article describes the ZLS study protocol and discusses opportunities, methodological and conceptual challenges, and limitations arising from a long-term longitudinal cohort recruited from a study about development in early life. In the future, the ZLS will provide data to investigate childhood antecedents of adult health outcomes and, ultimately, will help respond to the frequent call of scientists to shift the focus of aging research into the first decades of life and, thus, to take a lifespan perspective on aging. (shrink)

Higher education institutions worldwide have begun to embrace sustainability issues and engage their campuses and communities in such efforts, which have led to the development of integrity and ethical values in these organizations and their relationships with stakeholders. This study provides a literary review of the concept of University Social Responsibility (USR) and sustainability programs worldwide, grouped into eight research streams: conceptual framework, strategic planning and USR, educating on USR, spreading USR, reporting and USR, evaluation of USR, barriers and accelerators (...) and case studies. The aforementioned research streams served as a context to explore best practices in sustainability on a global basis. (shrink)

This book defends two main ideas: there is a need and a market for better specialised dictionaries for learners; we need a sound theoretical framework for coping with known and unknown challenges in the realm of pedagogical specialised lexicography. Both themes were Enrique Alcaraz's driving force during his life. Hence, his memory deserves this book that has been written by leading scholars in the field? they have compiled more than 70 dictionaries and published hundreds of books and articles on the (...) topics here discussed? although only two of them knew him in person. (shrink)

Italian Sounding—i. e., the Italian appearance of a product or service brand irrespective of its country of origin—represents a global market phenomenon affecting a wide range of economic sectors, particularly the agro-food sector. Although its economic impact has been repeatedly stressed from different points of view, systematic scientific knowledge regarding its social–psychological bases is lacking. Three studies carried out in three different countries address this literature gap. Different consumer groups are targeted regarding major product categories pre-selected categories, which are the (...) major Italian food goods within the specific country according to piloting. In each study, the main independent variable has been manipulated by presenting real product images, whose “Italianness” degree is effectively manipulated by the main study variable across three or four levels. Main hypotheses are tested via a survey with the specific product images administered to samples in Italy, China, and the USA. Across the three studies, results show that Made in Italy products, compared to the other ones, are advantaged in terms of the main dependent variables: reputation profile, general reputation, attitude, and willingness to pay. Moreover, Italian Sounding products are endowed with corresponding significant advantages when compared to the Generic Foreign by non-Italian samples. Results reveal the specific social–psychological profile of Italian Sounding products in terms of either weaknesses or strengths when compared to both Made in Italy products and Generic Foreign ones, differently in the eyes of Italian and non-Italian consumers across different countries. Finally, consistently across the three studies, the extent to which a food product is perceived to be Italian increases consumers' WTP for that product, and this effect is consistently mediated by the product's reputation. (shrink)

Platelets have important hemostatic functions in repairing blood vessels upon tissue injury. Cytokines, growth factors, and metabolites stored in platelet α‐granules and dense granules are released upon platelet activation and clotting. Emerging evidence indicates that such platelet‐derived signaling factors are instrumental in guiding tissue regeneration. Here, we discuss the important roles of platelet‐secreted signaling factors in skeletal muscle regeneration. Chemokines secreted by platelets in the early phase after injury are needed to recruit neutrophils to injured muscles, and impeding this early (...) step of muscle regeneration exacerbates inflammation at later stages, compromises neo‐angiogenesis and the growth of newly formed myofibers, and reduces post‐injury muscle force production. Platelets also contribute to the recruitment of pro‐regenerative stromal cells from the adipose tissue, and the platelet releasate may also regulate the metabolism and proliferation of muscle satellite cells, which sustain myogenesis. Therefore, harnessing the signaling functions of platelets and the platelet secretome may provide new avenues for promoting skeletal muscle regeneration in health and disease. (shrink)

This paper presents an intuitive explanation about why and how Rawlsian Theory of Justice (Rawls in A theory of justice, Harvard University Press, Harvard, 1971) provides the foundations to a solution for algorithmic bias. The contribution of the paper is to discuss and show why Rawlsian ideas in their original form (e.g. the veil of ignorance, original position, and allowing inequalities that serve the worst-off) are relevant to operationalize fairness for algorithmic decision making. The paper also explains how this leads (...) to a specific MinMaxfairness solution, which addresses the basic challenges of algorithmic justice. We combine substantive elements of Rawlsian perspective with an intuitive explanation in order to provide accessible and practical insights. The goal is to propose and motivate why and how the MinMaxfairness solution derived from Rawlsian principles overcomes some of the current challenges for algorithmic bias and highlight the benefits provided when compared to other approaches. The paper presents and discusses the solution by building a bridge between the qualitative theoretical aspects and the quantitative technical approach. (shrink)

The purpose of this scoping review is to investigate the value of creative arts therapies in healthy older adults. This article aims to shed light on current knowledge concerning the effectiveness of art therapies for the prevention of common age-related conditions using the definition of art therapy provided by the American Art Therapy Association, as well as Cohen’s conceptual framework for the psychological conceptualization of the relationship between the arts and health in later life. The objective is to carefully capture (...) subthreshold situations of distress, which are often not taken into account and primarily involve psychological aspects that are crucial in the multidimensional perspective of healthy aging. Twelve articles were selected and examined following an initial electronic search on 3 databases. A thematic analysis of the results identified four major themes: improving cognitive performance and proprioception; enhancing self-identity and meaningful life; reducing feelings of loneliness and depressive symptoms; and the importance of socialization. All these aspects constitute the basis for preventing psychological distress and enhancing mental well-being for healthy aging. (shrink)

Synaptophysin (Syp) was the first synaptic vesicle (SV) protein to be cloned. Since its discovery in 1985, it has been used by us and by many laboratories around the world as an invaluable marker to study the distribution of synapses in the brain and to uncover the basic features of the life cycle of SVs. Although single gene ablation of Syp does not lead to an overt phenotype, a large body of experimental data both in vitro and in vivo indicate (...) that Syp (alone or in association with homologous proteins) is involved in multiple, important aspects of SV exo‐endocytosis, including regulation of SNARE assembly into the fusion core complex, formation of the fusion pore initiating neurotransmitter release, activation of SV endocytosis and SV biogenesis. In this article, we summarise the main results of the studies on Syp carried out by our and other laboratories, and explain why we believe that Syp plays a major role in SV trafficking. BioEssays 26:445–453, 2004. © 2004 Wiley Periodicals, Inc. (shrink)

Análise dos processos de formação do professor. Situa inicialmente as alternativas de constituição dos agentes do sistema político administrativo da educação do final do período imperial para focalizar as estratégias formativas adotadas pela Escola Complementar, analisando para tanto entrevistas, documentos iconográficos e escritos. A delimitação espacial do estudo é a Província de São Pedro do Rio Grande do Sul, Brasil.

Discute a instrução pública a partir de seus agentes e os processos formativos de seleção, instrução, contratação, especialização e diferenciação que ao longo do tempo constituíram o professor contribuindo para a formação do cidadão e institucionalização da educação no Rio Grande do Sul.

This paper analyses the role of remorse and apology in international criminal trials by juxtaposing two prominent cases of convicted war criminals Biljana Plavšić and Esad Landžo. Plavšić was the first and only Bosnian Serb political leader to plead guilty before the International Criminal Tribunal for the former Yugoslavia. Her acknowledgement of guilt and purported remorse expressed during her ICTY proceedings was celebrated as a milestone for both the ICTY and the Balkans. However, she later retracted her remorse while serving (...) her prison sentence. Landžo was a guard at the notorious Čelebići detention camp and did not acknowledge his guilt publicly during his ICTY trial. Seven years after his release from prison, Landžo personally confronted survivors and apologised to them. Through comparison of these two widely different cases, we illustrate varying roles criminal trials can play in offender’s reflection on his/her crimes and how relevance and resonance of war criminal’s remorse in and outside of the courtroom depend on how remorse is expressed and to whom. (shrink)

This paper will analyse what it takes to conduct feminist and sensitive research in countries that have seen mass human rights violations. Transitional justice research involves critical examination of difficult topics which raises a number of ethical and methodological issues for both the participants and the researchers. Although empirical research has been a facet of the studies produced in the field, researchers’ accounts of undertaking research in often politically sensitive environments is largely missing from published books and research reports. This (...) paper is informed by personal experiences of doing research in wartime rape in the ethnically and politically divided country of Bosnia and Herzegovina. I argue that the researcher’s profile and positionality directly affects the fieldwork and that fieldwork is a dialogical process which is structured by the researcher and the wider political processes in the country. (shrink)

Parmenides and Melissus employ different deductive styles for their different kinds of argumentation. The former’s poem flows in an interesting sequence of passages: contents foreword, methodological premises, krisis, conclusions and corollaries. The latter, however, organizes an extensive process of deduction to show the characteristics of what is. In both cases, the strength of their argument rests on their deductive form, on the syntactical level of their texts: the formal structure of their reasonings help to identify the features and logical intersections (...) of their thoughts. On the one hand, Parmenides uses modal reasoning, enforcing the employment of the principle of the excluded middle. On the other hand, Melissus radicalizes the use of modal reasoning and employs counterfactual statements in order to develop his doctrine of what is. Despite their differences, both deserve a place in the Stone Age of logic and theory of argumentation due to their common ambition to demonstrate what is. (shrink)

In recent years, Reichenbach's 1920 conception of the principles of coordination has attracted increased attention after Michael Friedman's attempt to revive Reichenbach's idea of a "relativized a priori". This paper follows the origin and development of this idea in the framework of Reichenbach's distinction between the axioms of coordination and the axioms of connection. It suggests a further differentiation among the coordinating axioms and accordingly proposes a different account of Reichenbach's "relativized a priori".

This highly multidisciplinary collection discusses an increasingly important topic among scholars in science and technology studies: objectivity in science. It features eleven essays on scientific objectivity from a variety of perspectives, including philosophy of science, history of science, and feminist philosophy. Topics addressed in the book include the nature and value of scientific objectivity, the history of objectivity, and objectivity in scientific journals and communities. Taken individually, the essays supply new methodological tools for theorizing what is valuable in the pursuit (...) of objective knowledge and for investigating its history. The essays offer many starting points, while suggesting new avenues of research. Taken collectively, the essays exemplify the very virtues of objectivity that they theorize—in reading them together, the reader can sense various anxieties about the dangerously subjective in our age and locate commonalities of concern as well as differences of approach. As a result, the volume offers an expansive vision of a research community seeking a communal understanding of its own methods and its own epistemic anxieties, struggling to enunciate the key problems of knowledge of our time and offer insight into how to overcome them. -/- (Contributors: Alex Csiszar, Scott Edgar, Peter Galison, Ian Hacking, Sandra Harding, Moira Howes, Paolo Savoia, Judy Segal, Joan Steigerwald, and Alison Wylie). (shrink)

Resenha do livro Filosofia da Ancestralidade de Eduardo David de Oliveira.

Trata-se de investigar os tipos de tropas, tal como apresentados por Maquiavel, procurando compreender as características que destacam as tropas próprias. Feito isso, assumiremos o debate entre o que é público e o que é particular, tal como posto na Arte da Guerra, relacionando-o ao tema da guerra. Tal objetivo diz respeito à investigação anunciada por Maquiavel e que relaciona a vida civil à vida militar. Procurar-se-á mostrar a perspectiva do autor sobre o uso público da guerra tanto quanto as (...) consequências desastrosas de seu uso particular. Pretende-se, em tal percurso, evidenciar a guerra como ponto central do pensamento maquiaveliano, diretamente relacionada aos fundamentos da política, assim como o interesse de Maquiavel em pensar os problemas de seu tempo e abordá-los por uma perspectiva filosófica. A pesquisa se restringe a investigar o tema a partir do Príncipe, dos Discursos sobre a Primeira Década de Tito Lívio e da Arte da Guerra. (shrink)

This paper is the result of my participation in a discussion event of Problema. Anuario de filosofía y teoría del derecho entitled “The Construction of Precedent in Civil Law: Debates, Concepts and Challenges”. Several colleagues with a vast knowledge on the subject of judicial precedent participated in this seminar, which also delved into the widely debated aspects of judicial precedent focused on the case of Chile. The entire discussion aimed at proposing solutions, as well as shedding some light on some (...) of its important aspects.Starting from such transcendental concepts as, rationality and argumentative use, it is possible to find certain problems arising from the improper use of the above concepts, which in turn leads us to stare decisis, a term that if used incorrectly may result in an act against the internal independence of judges. (shrink)

Entendemos os eventuais problemas em discutir subjetividades a partir dos escritos de dois pensadores tão diferentes como Foucault e Winnicott, mas nesse estudo, o objetivo é fornecer um possível contraponto _winnicottiano_ para as análises realizadas por Foucault a respeito da subjetividade na racionalidade neoliberal. Nossa proposta é pensar a constituição da subjetividade na racionalidade política neoliberal, que conforme verificamos, constrói indivíduos psiquicamente voltados para certo individualismo em detrimento da ética e da alteridade. Após uma discussão sobre a dinâmica da formação (...) do capital humano, conforme apresentado por Foucault, e da apresentação das noções fundamentais acerca dessa constituição específica da subjetividade, realizamos um contraponto apresentando os pontos fundamentais da teoria do amadurecimento de Winnicott para pensar a respeito de possíveis consequências psíquicas que a racionalidade neoliberal, produtora de sujeitos voltados para a competição, impõe a essas estruturas subjetivas. (shrink)

El presente trabajo es el resultado de mi participación en el evento de discusión de la revista Problema. Anuario de Filosofía y Teoría del Derecho, que llevó por nombre “La construcción del precedente en el Civil Law: debates, conceptos y desafíos”, en el cual participaron varios colegas con un amplio conocimiento en el tema del precedente judicial; de igual forma, ahonda en los temas de mayor debate dentro de lo referente al precedente judicial, enfocado al caso chileno. Todo ello, con (...) la finalidad de proponer algunas soluciones al respecto, así como dilucidar ciertos aspectos importantes dentro del precedente. Partiendo de conceptos tan trascendentes como la prescriptibilidad, la racionalidad y el uso argumentativo, se logra llegar a ciertas problemáticas provocadas por el mal uso de los conceptos previamente mencionados, que a su vez nos conduce al stare decisis, término que mal utilizado puede resultar en un acto contrario a la independencia interna de la cual gozan los jueces. (shrink)

Olivera Cadahia, Luciana; Carrasco-Conde, Ana. Fuera de sí mismas. Motivos para dislocarse. Herder. 399 páginas.

High blood pressure (HBP) is a multifactorial clinical condition characterized by high and sustained levels of blood pressure (BP), and the presence of elevated BP in childhood is predictor of hypertension in adult life. Studies have shown a positive correlation between sodium chloride ingested in the diet and blood pressure values. This study aims to evaluate the consumption of added salt before and after awareness of risk, by high school students. This occurred for three days in the refectory, where students (...) received illustrative brochure with information about sodium intake; exhibition of a poster illustrating foods with their respective equivalent amount of sodium and sodium chloride, exemplifying the maximum recommended amount of consumption per day. For five days, before and after gaining awareness, it the amount of consumption of sachets of salt was accounted. Statistical analyzes were performed by Student's Test, with a confidence interval of 95%. During the study period were served on average 128.3 meals. Before the awareness of sodium consumption of risks, of 820mg and 330mg sodium salt was consumed an average per individual, and thereafter, 640mg and 260mg, respectively (p=0,043). Simple Nutrition Education Strategies in short term were effective for improving the consumption of added salt in adolescents. (shrink)

The organization of the Herodotian narrative is based overall in the characterization of the despotism, however this can only mean something in Herodotus‟ work if opposed to the Greek ways of political organization and mainly in relation to democracy. However, the fact that the barbarians‟ despotism takes higher evidence in the work is enough to make the theme of tyranny dominate over the poliada organization? Could not we assume that the distinction of tyranny would not be only one way to (...) show the Greeks their own particularity? In this case, the exotic one, marvelous and the admirable one would lie in the fact that the Greeks organized a completely singular way of political organization, stranger to all the other known peoples. (shrink)

In his Scientific Representation (2008), van Fraassen argues that measuring is a form of representation. In fact, every measurement pinpoints its target in accordance with specific operational rules within an already-constructed theoretical space, in which certain conceptual interconnections can be represented. Reichenbach’s 1920 account of coordination is particularly interesting in this connection. Even though recent reassessments of this account do not do full justice to some important elements lying behind it, they do have the merit of focusing on a different (...) aspect of his early work that traditional interpretations of relativized a priori principles have unfortunately neglected in favour of a more “structural” role for coordination. In Reichenbach’s early work, however, the idea of coordination was employed not only to indicate theory-specific fundamental principles such as the ones suggested in the literature on conventional principles in science, but also to refer to more “basic” assumptions. In Reichenbach, these principles are preconditions both of the individuation of physical magnitudes and of their measurement, and, as such, they are necessary to approach the world in the first instance. This paper aims to reassess Reichenbach’s approach to coordination and to the representation of physical quantities in light of recent literature on measurement and scientific representation. (shrink)

This paper formalizes an approach to the Internet of Things as a socio-technical system of systems and a part of the infosphere. It introduces a principle-based, human-centered approach to designing Internet of Things artifacts as elements of contextual cross-channel ecosystems. It connects the Internet of Things to the conceptualization of cross-channel ecosystems from current information architecture theory and practice, positing that the Internet of Things is both a formal, objective superset of any given ecosystem and a contextual, subjective subset of (...) specifically instantiated ecosystems. The paper argues for the necessity of a transdisciplinary theoretical framework to promote a human-centered generative understanding of the Internet of Things phenomena and their consequences, in accordance with the Metamodel Methodology. It proposes a phenomenology-grounded information architecture model detailing a set of 16 principles and secondary heuristics grouped according to an architectural perspective, which identifies guidelines that support the design of Internet of Things artifacts considering their objective characteristics; a human perspective, which identifies guidelines that support the design of Internet of Things artifacts considering subject/object relationships and the production of meaning; and a systemic perspective, which identifies guidelines that support the design of Internet of Things artifacts as relational parts of information-based ecosystems. These principles and guidelines are meant to provide the foundations for a practice-based approach to designing the Internet of Things–enabled information ecosystems. (shrink)

This paper formalizes an approach to the Internet of Things as a socio-technical system of systems and a part of the infosphere. It introduces a principle-based, human-centered approach to designing Internet of Things artifacts as elements of contextual cross-channel ecosystems. It connects the Internet of Things to the conceptualization of cross-channel ecosystems from current information architecture theory and practice, positing that the Internet of Things is both a formal, objective superset of any given ecosystem and a contextual, subjective subset of (...) specifically instantiated ecosystems. The paper argues for the necessity of a transdisciplinary theoretical framework to promote a human-centered generative understanding of the Internet of Things phenomena and their consequences, in accordance with the Metamodel Methodology. It proposes a phenomenology-grounded information architecture model detailing a set of 16 principles and secondary heuristics grouped according to an architectural perspective, which identifies guidelines that support the design of Internet of Things artifacts considering their objective characteristics; a human perspective, which identifies guidelines that support the design of Internet of Things artifacts considering subject/object relationships and the production of meaning; and a systemic perspective, which identifies guidelines that support the design of Internet of Things artifacts as relational parts of information-based ecosystems. These principles and guidelines are meant to provide the foundations for a practice-based approach to designing the Internet of Things–enabled information ecosystems. (shrink)

This paper formalizes an approach to the Internet of Things as a socio-technical system of systems and a part of the infosphere. It introduces a principle-based, human-centered approach to designing Internet of Things artifacts as elements of contextual cross-channel ecosystems. It connects the Internet of Things to the conceptualization of cross-channel ecosystems from current information architecture theory and practice, positing that the Internet of Things is both a formal, objective superset of any given ecosystem and a contextual, subjective subset of (...) specifically instantiated ecosystems. The paper argues for the necessity of a transdisciplinary theoretical framework to promote a human-centered generative understanding of the Internet of Things phenomena and their consequences, in accordance with the Metamodel Methodology. It proposes a phenomenology-grounded information architecture model detailing a set of 16 principles and secondary heuristics grouped according to an architectural perspective, which identifies guidelines that support the design of Internet of Things artifacts considering their objective characteristics; a human perspective, which identifies guidelines that support the design of Internet of Things artifacts considering subject/object relationships and the production of meaning; and a systemic perspective, which identifies guidelines that support the design of Internet of Things artifacts as relational parts of information-based ecosystems. These principles and guidelines are meant to provide the foundations for a practice-based approach to designing the Internet of Things–enabled information ecosystems. (shrink)